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ea0085p61 | Diabetes 3 | BSPED2022

GAME-SET-MATCH mnemonic: an infographic to teach effective dynamic glucose management strategies improving time in range in children with type 1 diabetes using continuous glucose monitoring

Pemberton John S , Dias Renuka P , Barrett Timothy G , Kershaw Melanie , Krone Ruth , Uday Suma

Background: Continuous Glucose Monitoring (CGM) is now becoming the standard of care for children and young people with diabetes (CYPD). Due to a lack of validated education programmes, we created The CGM Academy delivering evidence-based structured education. The results of the first 50 CYPD graduating from the academy demonstrated statistically significant improvement in time in range (TIR, 3.9-10.0 mmol/l) by 8.3% (P<0.001) and HbA1c by 3.8 mmol/mol...

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ea0034p357 | Steroids | SFEBES2014

Steroid sulfatase contributes to systemic androgen activation in pre-pubertal boys: lessons from steroid sulfatase deficiency

Idkowiak Jan , Taylor Angela E , O'Neil Donna M , Subtil Sandra , Vijzelaar Raymon , Dias Renuka P , Amin Rakesh , Barrett Timothy G , Kirk Jeremy W , Shackleton Cedric H L , Moss Celia , Arlt Wiebke

Steroid sulfatase (STS) cleaves the sulfate moiety off steroid sulfates, including DHEAS, the inactive sulfate ester of the adrenal androgen precursor DHEA. Deficient DHEA sulfation, the opposite enzymatic reaction to that catalysed by STS, results in androgen excess by increased conversion of DHEA to active androgens. STS deficiency (STSD) due to deletions or inactivating mutations in the X-linked STS gene manifests with ichthyosis, but androgen homeostasis in STSD h...

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Endocrine Abstracts

GAME-SET-MATCH mnemonic: an infographic to teach effective dynamic glucose management strategies improving time in range in children with type 1 diabetes using continuous glucose monitoring

Steroid sulfatase contributes to systemic androgen activation in pre-pubertal boys: lessons from steroid sulfatase deficiency

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